Typically a trade-off needs to be aimed for, that optimizes noise reduction at the cost of restricted effect size loss. Another widespread problem in longitudinal picture processing is the, often unintentional, introduction of processing bias. When, for example, comply with-up photographs get registered and resampled to the baseline picture, interpolation artifacts get introduced to solely the comply with-up photos and not the baseline. These artifact may cause spurious results (often a bias in the direction of overestimating longitudinal change and thus underestimating required pattern size). In the event you loved this short article and you would love to receive much
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